The molecular fingerprint of bladder cancer in blood - Karin Birkenkamp-Demtröder

Developments within bioscience have boomed in recent years. New methods and techniques are constantly being created which revolutionize our knowledge of health and disease in humans. Are you interested in hearing more about developments in Bioscience? Are you speculating about what knowledge is going to make a revolutionary difference to human health and disease prevention? Join us on an expedition into the body for this year's "Exploring Bioscience" and get an exclusive insight into the ground-breaking advances in natural science. This is the second video out of six at the Exploring Bioscience 2022 event.

The Molecular fingerprint of bladder cancer with Karin Birkenkamp-Demtröder

Human blood contains cell free DNA (cfDNA), small fragments of DNA originating from cellular breakdown of healthy cells. In cancer patients, a tiny fraction of circulating tumor DNA (ctDNA) shedded from cancer cells maybe present among the huge number of cfDNA fragments. ctDNA contains mutations which match the mutations in the cancer cells they are originating from, e.g. disseminated cells. Thus, the population of ctDNA in the blood of a patient resembles a characteristic tumor- and patient specific fingerprint. As the half-life of cfDNA / ctDNA in circulation is less than two hours, real time tumor dynamics can be tracked hereby informing about the current state of the disease. The presence of ctDNA in the blood is prognostic and ctDNA analysis can be used e.g. to detect minimal residual disease to monitor treatment response or to identify actionable targets for personalized treatment approaches.

In this video, Karin Birkenkamp-Demtröder will present and tell you more about this subject. Karin Birkenkamp-Demtröder, PhD Associate Professor at The Department of Clinical Medicine at Aarhus University, is a pioneer in circulating tumor DNA research in bladder cancer, addressing early detection of minimal residual disease as well as monitoring of treatment response. She is committed to developing “precision medicine” approaches based on the unique molecular profile of each patient’s tumor to the benefit of patients with bladder cancer.

The program for the event ‘Exploring Bioscience 2022’

At Exploring Bioscience 2022, you will hear several speakers, all of whom will enlighten you on various topics. At Exploring Bioscience 2022, you will hear about, among other things, how intestinal bacteria affect people's mental and physical health. You will hear about how cancer recurrence can be detected early, several months before it can be seen on a scan.

This is just some of what you will hear more about at Exploring Bioscience 2022 – Does this sound interesting to you? Then listen to this video and hear some of the following speakers at Exploring Bioscience:

•        ’Mikrobiomets univers åbner sig’ with Professor Oluf Borbye Pedersen
  
  
•        ‘The molecular fingerprint of bladder cancer in blood’ with PhD Associate Professor Karin Birkenkamp-Demtröder
  
  
•        ’Gå ind i hjernen og rygmarven, og se hvordan vi bevæger os’ with Professor  viceinstitutleder Ole Kiehn
  
  
•        ‘T cells: A living drug against cancer’ with Professor and leader of national center for cancer immunterapi, Özcan Met
  
  
•        ’Sekventering af arvemassen hos os alle’ with Professor Mikkel Heide Schierup
  
  
•        ’Hvordan lever man længere?’ with Author and MSc in Biotechnology Nicklas Brendborg